PUBLICATIONS & DATA

Genomic and proteomic data can be accessed by following the links provided in the Data column on this page or through the Katze Lab Informatics Server.

For questions about or assistance with data access, please contact: help@viromics.washington.edu.

Authors Title Citation Data
2008
Baas, T., A. Roberts, T.H. Teal, L. Vogel, J. Chen, T.M. Tumpey, M.G. Katze, and K. Subbarao Genomic analysis reveals age-dependent innate immune responses to SARS coronavirus J. Virol. In press  
Borozan, I., L. Chen, B. Paeper, J.E. Heathcote, A.M. Edwards, M. Katze, Z. Zhang, and I.D. McGilvray MAID: an effect-sized based model for microarray data integration across laboratories and platforms BMC Bioinformatics 9:305  
Katze, M.G., J.L. Fornek, R.E. Palermo, K.-A. Walters, and M.J. Korth Innate immune modulation by RNA viruses: emerging insights from functional genomics Nature Rev. Immunol. 8:644-654  
2007
Baskin, C.R., H. Bielefeldt-Ohmann, A. Garcia-Sastre, T.M. Tumpey, N. Van Hoeven, V.S. Carter, M.J. Thomas, S. Proll, A. Solorzano, R. Billharz, J.L. Fornek, S. Thomas, C.H. Chen, E.A. Clark, M.K. Kaja, and M.G. Katze Functional genomic and serological analysis of the protective immune response resulting from vaccination of macaques with an NS1-truncated influenza virus J. Virol. 81:11817-11827 Informatics Server
Chan, E. Y., W. J. Qian, D. L. Diamond, T. Liu, M. A. Gritsenko, M. E. Monroe, D. G. Camp, R. D. Smith, and M. G. Katze Quantitative analysis of HIV-1 infected CD4+ cell proteome: dysregulated cell cycle progression and nuclear transport coincide with robust virus production J. Virol 81:7571-7583 Informatics Server
de Lang, A., T. Baas, T. Teal, L. M. Leijten, B. Rain, A. D. Osterhaus, B. L. Haagmans, and M. G. Katze Functional genomics highlights differential induction of antiviral pathways in the lungs of SARS-CoV-infected macaques PLoS Pathog. 3:e112 Informatics Server
Diamond, D. L., J. M. Jacobs, B. Paeper, S. C. Proll, M. A Gritsenko, R. L, Carithers, A. M. Larson, D. G. Camp, R. D. Smith, and M. G. Katze Proteomic profiling of human liver biopsies: hepatitis C virus-induced fibrosis and mitochondrial dysfunction Hepatology 46:649-657 Informatics Server
Fornek, J. L., M. J. Korth, and M. G. Katze Use of functional genomics to understand influenza virus-host interactions Adv. Virus Res. 70:81-100  
Frederickson, B. L., B. C. Keller, J. Fornek, M. G. Katze, and M. Gale, Jr. Establishment and maintenance of the innate antiviral response to West Nile Virus involves both RIG-I and MDA5 signaling through IPS-1 J. Virol. 82:609-616  
Gibbs, R., J. Rogers, M. G. Katze, et al. Evolutionary and biomedical insights from the rhesus macaque genome Science 316: 222-234  
Goodman, A. G., J. A. Smith, S. Balachandran, O. Perwitasari, S. C. Proll, M. J. Thomas, M. J. Korth, G. N. Barber, L. A. Schiff, and M. G. Katze The cellular protein P58IPK regulates influenza virus mRNA translation and replication through a PKR-mediated mechanism J. Virol 81:2221-2230  
Katze, M. G. and M. J. Korth Lost in the world of functional genomics, systems biology, and translational research: Is there life after the Milstein award? Cytokine Growth Factor Rev. 18:441-450  
Kobasa, D., S. M. Jones, K. Shinya, J. C. Kash, J. Copps, H. Ebihara, Y. Hatta, J. H. Kim, P. Halfmann, M. Hatta, F. Feldmann, J. B. Alimonti, L. Fernando, Y. Li, M. G. Katze, H. Feldmann, and Y. Kawaoka Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus Nature 445:319-323 Informatics Server

Array Express
Li, Y., E. Y. Chan, and M. G. Katze Functional genomics analyses of differential macaque peripheral blood mononuclear cell infections by human immunodeficiency virus-1 and simian immunodeficiency virus Virology 366:137-149 Informatics Server
Loo, Y. M., J. Fornek, N. Crochet, G. Bajwa, O. Perwitasari, L. Martinez-Sobrido, S. Akira, M. A. Gill, A. Garcia-Sastre, M. G. Katze, and M Gale, Jr. Distinct RIG-I and MDA5 signaling by RNA viruses in innate immunity J. Virol. 82:335-345  
Rutkowski, D. T., S. W. Kang, A. G. Goodman, J. L. Garrison, J. Taunton, M. G. Katze, R. J. Kaufman, and R. S. Hegde The role of p58IPK in protecting the stressed endoplasmic reticulum Mol. Biol. Cell 18:3681-3691  
Tan, S.-L., G. Ganji, B. Paeper, S. Proll, and M. G. Katze Systems biology and the host response to infection Nature Biotechnol. 25:1383-1389  
Tang, W., C. Lazaro, J. Campbell, T. Parks, M. G. Katze, and N. Fausto Response of non-transformed human hepatocytes to conditional expression of full-length hepatitis C virus open reading frame Am. J. Pathol. 171:1831-1846  
Wallace, J. C., M. J. Korth, B. W. Paeper, S. C. Proll, M. J. Thomas, C. L. Magness, S. P. Iadonato, C. Nelson, and M. G. Katze High-density rhesus macaque oligonucleotide microarray design using early-stage rhesus genome sequence information and human genome annotations BMC Genomics 8:28 Informatics Server

Array Express
2006 TOP
Baas, T., C. R. Baskin, D. L. Diamond, A. Garcia-Sastre, H. Bielefeldt-Ohmann, T. M. Tumpey, M. J. Thomas, V. S. Carter, T. H. Teal, N. Van Hoeven, S. C. Proll, J. M. Jacobs, Z. R. Caldwell, M. A. Gritsenko, R. R. Hukkanen, D. G. Camp, R. D. Smith,and M. G. Katze Integrated molecular signature of disease: analysis of influenza virus-infected macaques through functional genomics and proteomics J. Virol. 80:10813-10828 Informatics Server

NCRR Proteomics
Baas, T., J. Taubenberger, P. Y. Chong, P. Chui, and M. G. Katze SARS-CoV virus-host interactions and comparative etiologies of acute respiratory distress syndrome as determined by transcriptional and cytokine profiling of formalin-fixed paraffin-embedded tissues J. Interferon Cytokine Res. 26:309-317  
Diamond, D. L., S. C. Proll, J. M. Jacobs, E. Y. Chan, D. G. Camp, R. D. Smith, and M. G. Katze HepatoProteomics: applying proteomic technologies to the study of liver function and disease. Hepatology 44:299-308  
Kash, J. C., A. G. Goodman, M. J. Korth, and M. G. Katze Hijacking of the host-cell response and translational control during influenza virus infection Virus Res. 119:111-120  
Kash, J. C., E. Mühlberger, V. Carter, O. Grosch, O. Perwitasari, S. C. Proll, M. J. Thomas, F. Weber, H.-D. Klenk, and M. G. Katze Global suppression of the host antiviral response by Ebola- and Marburgviruses: increased antagonism of the type 1 interferon response is associated with enhanced virulence J. Virol. 80:3009-3020 Informatics Server
Kash, J. C., T. M. Tumpey, S. C. Proll, V. Carter, O. Perwitasare, M. J. Thomas, C. F. Basler, P. Palese, J. K. Taubenberger, A. Garcia-Sastre, D. E. Swayne, and M. G. Katze Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus Nature 443:578-581 Informatics Server
Korth, M. J., J. C. Kash, C. R. Baskin, and M. G. Katze Insights into influenza virus-host interactions through global gene expression profiling: cell culture systems to animal models, p. 341-360. In Y. Kawaoka (ed.), Influenza virology: current topics Horizon Scientific Press, Wymondham, U.K.  
Lederer, S. L., K. A. Walters, S. Proll, B. Paeper, S. Robinzon, L. Boix, N. Fausto, J. Bruix, and M. G. Katze Distinct cellular responses differentiating alcohol- and hepatitis C virus-induced liver cirrhosis Virol. J. 3:98 Informatics Server
Langland, J. O., J. C. Kash, V. Carter, M. J. Thomas, M. G. Katze, and B. L. Jacobs Suppression of proinflammatory signal transduction and gene expression by the dual nucleic acid binding domains of the vaccinia virus E3L proteins J. Virol. 80:10083-10095 Informatics Server

Array Express
Oyadomari, S., C. Yun, E. A. Fisher, N. Kreglinger, G. Kreibich, M. Oyadomari, H. P. Harding, A. G. Goodman, H. Harant, J. L. Garrison, J. Taunton, M. G. Katze, and D. Ron Cotranslocational degradation protects the stressed endoplasmic reticulum from protein overload Cell 126:727-739  
Pasieka, T. J., T. Baas, V. S. Carter, S. C. Proll, D. A. Leib, and M. G. Katze Functional genomics analysis of herpes simplex virus type 1 counteraction of the host innate response. J. Virol. 80:7600-7612 Informatics Server
Smith, J. A., S. C. Schmechel, A. Raghavan, M. Abelson, C. Reilly, M. G. Katze, R. J. Kaufman, P. R. Bohjanen, and L. A. Schiff Reovirus induces and benefits from an integrated cellular stress response J. Virol. 80:2019-2033  
Smith, M. W., K.-A. Walters, M. J. Korth, M. Fitzgibbon, S. C. Proll, J. C. Thompson, M. M. Yeh, M. C. Shuhart, J. C. Furlong, P. P. Cox, D. L. Thomas, J. D. Phillips, J. P. Kushner, N. Fausto, R. L. Carithers, and M. G. Katze Gene expression patterns that correlate with hepatitis C and early progression to fibrosis in liver transplant recipients Gastroenterol. 130:179-187 Informatics Server
Thomas, M. J., M. B. Agy, S. C. Proll, B. W. Paeper, Y. Li, K. L. Jensen, M. J. Korth, and M. G. Katze Functional gene analysis of individual response to challenge with simian immunodeficiency virus SIVmac239 in Macaca mulatta peripheral blood mononuclear cell culture. Virology 348:242-252 Informatics Server
Thomas, M. J., L. R. Flanary, B. A. Brown, M. G. Katze, and C. R. Baskin Use of human nasal cannulas during bronchoscopy procedures as a simple method for maintaining adequate oxygen saturation in pigtailed macaques (Macaca nemestrina) J. Am. Assoc. Lab Anim. Sci. 45:44-48  
Wallace, J. C., M. J. Korth, D. L. Diamond, S. C. Proll, and M. G. Katze Virology in the 21st century: finding function with functional genomics Future Virol. 1:47-53.  
Walters, K. A., M. A. Joyce, J. C. Thompson, S. Proll, J. Wallace, M. W. Smith, J. Furlong, D. L. Tyrrell, and M. G. Katze Application of functional genomics to the chimeric mouse model of HCV infection: optimization of microarray protocols and genomics analysis. Virol. J. 3:37 Informatics Server
Walters, K. A., M. A. Joyce, J. C. Thompson, M. W. Smith, M. M. Yeh, S. Proll, L.-F. Zhu, T. J. Gao, N. M. Knetman, D. L. Tyrrell, and M. G. Katze Host-specific response to HCV infection in the chimeric SCID-beige/Alb-uPA mouse model: role of the innate antiviral immune response PLoS Pathogens 2:591-601 Informatics Server
Walters, K. A., M. W. Smith, S. Pal, J. C. Thompson, M. J. Thomas, M. M. Yeh, D. L. Thomas, M. Fitzgibbon, S. Proll, N. Fausto, D. R. Gretch, R. L. Carithers, Jr., M. C. Shuhart, and M. G. Katze Identification of a specific gene expression pattern associated with HCV-induced pathogenesis in HCV- and HCV/HIV-infected individuals Virology 350:453-464 Informatics Server
2005 TOP
Desiere, F., E. W. Deutsch, A. I. Nesvizhskii, P. Mallick, N. L. King, J. K. Eng, A. Aderem, R. Boyle, E. Brunner, S. Donohoe, N. Fausto, E. Hafen, L. Hood, M. G. Katze, K. A. Kennedy, F. Kregenow, H. Lee, B. Lin, D. Martin, J. A. Ranish, D. J. Rawlings, L. E. Samelson, Y. Shiio, J. D. Watts, B. Wollscheid, M. E. Wright, W. Yan, L. Yang, E. C. Yi, H. Zhang, and R. Aebersold Integration with the human genome of peptide sequences obtained by high-throughput mass spectrometry Genome Biol. 6:R9.  
Furlong, C.E., R.C. Stevens, S.D. Soelberg, N. Yee, G. Geiss, M.G. Katze, S. Near, S. Yee, and T. Chinowsky Adaptation of near real time biosensor systems for monitoring of cabin air quality, p. 1–16. In: C. Winder (ed.), Proceedings of the contaminated air protection conference. University of New South Wales, Sydney    
Jacobs, J.M., D.L. Diamond, E.Y. Chan, M.A. Gritsenko, W. Qian, M. Stastna, T. Baas, D.G. Camp II, R.L. Carithers Jr., R.D. Smith, and M.G. Katze Proteome analysis of liver cells expressing a full-length hepatitis C virus (HCV) replicon and biopsy specimens of posttransplantation liver from HCV-infected patients J. Virol. 79:7558-7569 Informatics Server

NCRR Proteomics
Korth, M.J., J.C. Kash, J.C. Furlong, and M.G. Katze Virus infection and the interferon response: a global view through functional genomics Methods Mol. Med. 116:37–55  
Ladiges W.C., S.E. Knoblaugh, J.F. Morton, M.J. Korth, B.L. Sopher, C.R. Baskin, A. MacAuley, A.G. Goodman, R.C. LeBoeuf, and M.G. Katze Pancreatic β-cell failure in mice with a deletion mutation of the endoplasmic reticulum molecular chaperone gene P58IPK Diabetes. 54:1071-1081  
Magness, C.L., P.C. Fellin, M.J. Thomas, M.J. Korth, M.B. Agy, S.C. Proll, M. Fitzgibbon, C.S. Scherer, D.G. Miner, M.G. Katze, and S.P. Iadonato Analysis of the Macaca mulatta transcriptome and the sequence divergence between Macaca and human Genome Biol. 6:R60. Informatics Server

Array Express
2004 TOP
Baskin, C.R., A. García-Sastre, T.M. Tumpey, H. Bielefeldt-Ohmann, V.S. Carter, E. Nistal-Villán, and M.G. Katze Integration of clinical data, pathology, and cDNA microarrays in influenza virus-infected pigtailed macaques (Macaca nemestrina) J. Virol. 78:10420-10432 Informatics Server
Coito, C., D.L. Diamond, P. Neddermann, M.J. Korth, and M.G. Katze High-throughput screening of the yeast kinome: identification of human serine/theronine kinases that phosphorylate the hepatitis C virus NS5A protein J. Virol. 78:3502-3513  
Fredericksen, B. L., M. Smith, M. G. Katze, P. Y. Shi, and M. Gale, Jr. The host response to West Nile Virus infection limits viral spread through the activation of the interferon regulatory factor 3 pathway J. Virol. 78:7737-7747  
Kash J.C., C.F. Basler, A. García-Sastre, V. Carter, R. Billharz, D.E. Swayne, R.M. Przygodzki, J.K. Taubenberger, M.G. Katze, and T.M. Tumpey Global host immune response: pathogenesis and transcriptional profiling of type A influenza viruses expressing the hemagglutinin and neuraminidase genes from the 1918 pandemic virus J. Virol. 78:9499-9511 Informatics Server
Yan, W., H. Lee, E. W. Deutsch, C. A. Lazaro, W. Tang, E. Chen, N. Fausto, M. G. Katze, and R. Aebersold A dataset of human liver proteins identified by protein profiling via isotope coded affinity tag (ICAT) and tandem mass spectrometry Mol. Cell Proteomics. 3:1039-1041  
Yan, W., H. Lee, E.C. Yi, D. Reiss, P. Shannon, B.K. Kwieciszewski, C. Coito, X.-J. Li, A. Keller, J. Eng, T. Galitski, D.R. Goodlett, R. Aebersold, and M.G. Katze System-based proteomic analysis of the interferon response in human liver cells Genome Biol. 5:R54  
2003 TOP
Geiss, G.K., V.S. Carter, Y. He, B.K. Kwieciszewski, T. Holzman, M.J. Korth, C.A. Lazaro, N. Fausto, R.E. Bumgarner, and M.G. Katze Gene expression profiling of the cellular transcriptional network regulated by alpha/beta interferon and its partial attenuation by the hepatitis C virus nonstructural 5A protein. J. Virol. 77:6367-6375 Informatics Server
He, Y., W. Yan, C. Coito, Y. Li, M. Gale, and M.G. Katze The regulation of hepatitis C virus (HCV) internal ribosome- entry site-mediated translation by HCV replicons and nonstructural proteins. J. Gen. Virol. 84:535-543 PDF
Smith, M.W., Z.N. Yue, G.K. Geiss, N.Y. Sadovnikova, V.S. Carter, L. Boix, C.A. Lazaro, G.B. Rosenberg, R.E. Bumgarner, N. Fausto, J. Bruix, and M.G. Katze Identification of novel tumor markers in hepatitis C virus-associated hepatocellular carcinoma. Cancer Res. 63:859-864 Informatics Server
Smith, M.W., Z.N. Yue, M.J. Korth, H.A. Do, L. Boix, N. Fausto, J. Bruix, R.L. Carithers Jr., and M.G. Katze Hepatitis C virus and liver disease: global transcriptional profiling and identification of potential markers. Hepatology. 38:1458-1467 Informatics Server
van 't Wout, A.B., G.K. Lehrman, S.A. Mikheeva, G.C. O'Keeffe, M.G. Katze, R.E. Bumgarner, G.K. Geiss, and J.I. Mullins Cellular gene expression upon human immunodeficiency virus type 1 infection of CD4+-T-cell lines. J. Virol. 77:1392-1402. Informatics Server
2002 TOP
Gale, M. Jr., C.M. Blakely, A. Darveau, P.R. Romano, M.J. Korth, and M.G. Katze P52rIPK regulates the molecular co-chaperone P58IPK to mediate control of the RNA-dependent protein kinase in response to cytoplasmic stress. Biochemistry. 41:11878-11887  
Geiss, G.K., M. Salvatore, T.M. Tumpey, V.S. Carter, X. Wang, C.F. Basler, J.K. Taubengerger, R.E. Bumgarner, P. Palese, M.G. Katze, and A. García-Sastre Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: the role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza. Proc. Natl. Acad. Sci. USA. 99:10736-10741 Informatics Server

PDF
He, Y. and M.G. Katze To interfere and to anti-interfere: the interplay between hepatitis C virus and interferon. Viral Immunol. 15:95-119  
He, Y., H. Nakao, S.-L. Tan, S.J. Polyak, P. Neddermann, S. Vijaysri, B.L. Jacobs, and M.G. Katze Subversion of cell signaling pathways by hepatitis C virus nonstructural 5A protein via interaction with Grb2 and P85 phosphatidylinositol 3-kinase. J. Virol. 76:9207-9217 PDF
Kash, J.C., D.M. Cunningham, M.W. Smit, Y.-W. Park, D. Fritz, J. Wilusz, and M.G. Katze Selective translation of eukaryotic mRNAs: a functional molecular analysis of GRSF-1, a positive regulator of influenza virus protein synthesis. J. Virol. 76:10417-10426 PDF
Katze, M.G. Interferon, PKR, virology, and genomics: what is past and what is next in the new millennium? J. Interferon Cytokine Res. 22:283-286  
Katze, M.G., Y. He, and M. Gale Jr. Viruses and interferon: a fight for supremacy. Nat. Rev. Immunol. 2:675-687 PDF
Korth, M.J. and M.G. Katze Unlocking the mysteries of virus-host interactions: does functional genomics hold the key? Ann. N. Y. Acad. Sci. 975:160-168  
Tan, S.-L. and M.G. Katze PKR RNA-dependent protein kinase (human) p. 2512-2514. In Wiley Encyclopedia of Molecular Medicine, John Wiley & Sons, Inc., New York.  
Tan, S.-L., S.U. Tareen, M.W. Melville, C.M. Blakely, and M.G. Katze The direct binding of the catalytic subunit of protein phosphatase 1 to the PKR protein kinase is necessary but not sufficient for inactivation and disruption of enzyme dimer formation. J. Biol. Chem. 277:36109-36117  
Yan, W., C.L. Frank, M.J. Korth, B.L. Sopher, I. Novoa, D. Ron, and M.G. Katze Control of PERK eIF2α kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58IPK. Proc. Natl. Acad. Sci. USA. 99:15920-15925  
Yan, W., M.J. Gale Jr., S.-L. Tan, and M.G. Katze Inactivation of the PKR protein kinase and stimulation of mRNA translation by the cellular co-chaperone P58IPK does not require J-domain function. Biochemistry. 41:4938-4945  
2001 TOP
Geiss, G., J. Ge, J. Guo, R. Bumgarner, M.G. Katze, and G.C. Sen A comprehensive view of gene expression by double-stranded RNA-mediated cell signaling. J. Biol. Chem. 276:30178-30182  
Geiss, G.K., M.C. An, R.E. Bumgarner, E. Hammersmark, D. Cunningham, and M.G. Katze Global impact of influenza virus on cellular pathways is mediated by both replication-dependent and -independent events. J. Virol. 75:4321-4331  
He, Y, S.-L. Tan, S.U. Tareen, S. Vijaysri, J.O. Langland, B.L. Jacobs, and M.G. Katze Regulation of mRNA translation and cellular signaling by hepatitis C virus nonstructural protein NS5A. J. Virol. 75:5090-5098  
Tan, S.-L. and M.G. Katze How hepatitis C virus counteracts the interferon response: the jury is still out on NS5A. Virology. 284:1-12  
2000 TOP
Gale, M., Jr., S.-L. Tan, and M.G. Katze Translational control of viral gene expression in eukaryotes. Microbiol. Mol. Biol. Rev. 64:239-280  
Geiss, G.K., R.E. Bumgarner, M. An, M.B. Agy, A.B. van't Wout, E. Hammersmark, V. Carter, D. Upchurch, J.I. Mullins, and M.G. Katze Large-scale monitoring of host cell gene expression during HIV-1 infection using cDNA microarrays. Virology. 266:8-16  
Katze, M.G., B. Kwieciszewski, D.R. Goodlett, C.M. Blakely, P. Neddermann, S.-L. Tan, and R. Aebersold Ser2194 is a highly conserved major phosphorylation site of the hepatitis C virus nonstructural protein NS5A. Virology. 278:501-513  
Korth, M.J. and M.G. Katze Evading the interferon response: hepatitis C virus and the interferon-induced protein kinase, PKR. Curr. Top. Microbiol. Immunol. 242:197-224  
Korth, M.J., S.-L. Tan, and M.G. Katze Modulation of intracellular signaling pathways and therapeutic response by hepatitis C virus. p. 45-53. In H.P. Dienes, P. Schirmacher, C. Brechot, and K. Okuda. (ed.), Chronic hepatitis: new concepts of pathogenesis, diagnosis and treatment. Kluwer Academic Publishers, Lancaster, UK.  
Melville, M.K., M.G. Katze, and S.-L. Tan P58IPK, a novel cochaperone containing tetratricopeptide repeats and a J-domain with oncogenic potential. Cell. Mol. Life Sci. 57:311-322  
Tan, S.-L., M.G. Katze, and M.J. Gale Translational reprogramming during influenza virus infection p. 933-950. In N. Sonenberg, J.W.B. Hershey, and M.B. Mathews (ed.), Translational control of gene expression. Cold Spring Harbor Laboratory Press, Plainview, N.Y.  
Tan, S.-L. and M.G. Katze HSV.com: maneuvering the internetworks of viral neuropathogenesis and evasion of the host defense. Proc. Natl. Acad. Sci. 97:5684-5686  
1999 TOP
Gale, M., Jr., B. Kwieciszewski, M. Dossett, H. Nakao, and M.G. Katze Antiapoptotic and oncogenic potentials of hepatitis C virus are linked to interferon resistance by viral repression of the PKR protein kinase. J. Virol. 73:6506-6516.  
Melville, M.W., S.-L. Tan, M. Wambach, J. Song, R.I. Morimoto, and M.G. Katze The cellular inhibitor of the PKR protein kinase, P58IPK, is an influenza virus-activated co-chaperone that modulates heat shock protein 70 activity. J. Biol. Chem. 274:3797-3803  
Park, Y.-W., S.-L. Tan, and M.G. Katze Differential sensitivity to 5-fluoro-orotic acid as a screen for bait RNA-independent false positives in a yeast three-hybrid system. Biotechniques. 26:1102-1106.  
Park, Y.-W., J. Wilusz, and M.G. Katze Regulation of eukaryotic protein synthesis: selective influenza viral mRNA translation is mediated by the cellular RNA-binding protein GRSF-1. Proc. Natl. Acad. Sci. USA. 96:6694-6699  
Tan, S.-L. and M.G. Katze The emerging role of the interferon-induced PKR protein kinase as an apoptotic effector: a new face of death? J. Interferon Cytokine Res. 19:543-554  
Tan, S.-L., H. Nakao, Y. He, V. Vijaysri, P. Neddermann, B.L. Jacobs, B.J. Mayer, and M.G. Katze NS5A, a nonstructural protein of hepatitis C virus, binds growth factor receptor-bound protein 2 adaptor protein in a Src homology 3 domain/ligand-dependent manner and perturbs mitogenic signaling. Proc. Natl. Acad. Sci. USA. 96:5533-5538  
Tang, N.M., M.J. Korth, M. Gale, Jr., M. Wambach, S.D. Der, S.K. Bandyopadhyay, B.R.G. Williams, and M.G. Katze Inhibition of double-stranded RNA- and tumor necrosis factor alpha-mediated apoptosis by tetratricopeptide repeat protein and cochaperone, P58IPK. Mol. Cell. Biol. 19:4757-4765  
1998 TOP
Gale, M., Jr., C.M. Blakely, D.A. Hopkins, M.W. Melville, M. Wambach, P.R. Romano, and M.G. Katze Regulation of interferon-induced protein kinase PKR: modulation of P58IPK inhibitory function by a novel protein, P52rIPK. Mol. Cell. Biol. 18:859-871  
Gale, M., Jr., C.M. Blakely, B. Kwieciszewski, S.-L. Tan, M. Dossett, M.J. Korth, S.J. Polyak, D.R. Gretch, and M.G. Katze Control of PKR protein kinase by hepatitis C virus nonstructural 5A protein: molecular mechanisms of kinase regulation. Mol. Cell. Biol. 18:5208-5218  
Gale, M., Jr. and M.G. Katze Molecular mechanisms of interferon resistance mediated by viral-directed inhibition of PKR, the interferon-induced protein kinase. Pharmacol. Ther. 78:29-46  
Gale, M., Jr., M.J. Korth, and M.G. Katze Repression of the PKR protein kinase by hepatitis C virus: a potential mechanism for interferon resistance. Clin. Diag. Virol. 10:157-162  
Korth, M.J., M.D. Taylor, and M.G. Katze Interferon inhibits the replication of HIV-1, SIV, and SHIV chimeric viruses by distinct mechanisms. Virology. 247:265-273  
Romano, P.R., F. Zhang, S.-L. Tan, M.T. Garcia-Barrio, M.G. Katze, T.E. Dever, and A.G. Hinnebusch Inhibition of double-stranded RNA-dependent protein kinase PKR by vaccinia virus E3: role of complex formation and the E3 N-terminal domain. Mol. Cell. Biol. 18:7304-7316  
Tan, S.-L., M. Dossett, and M.G. Katze Cryopreserved yeast cells suitable for routine, small-scale transformations. BioTechniques. 25:792-793  
Tan, S.-L., M.J. Gale, Jr., and M.G. Katze Double-stranded RNA-independent dimerization of interferon-induced protein kinase PKR and inhibition of dimerization by the cellular P58IPK inhibitor. Mol. Cell. Biol. 18:2431-2443  
Tan, S.-L. and M.G. Katze Biochemical and genetic evidence for complex formation between the influenza A virus NS1 protein and the interferon-induced PKR protein kinase. J. Interferon Cytokine Res. 18:757-766  
Tan, S.-L. and M.G. Katze Using genetic means to dissect homologous and heterologous protein-protein interactions of PKR, the interferon-induced protein kinase. Methods: Companion Methods Enzymol. 15:207-223  
Taylor, M.D., M.J. Korth, and M.G. Katze Interferon treatment inhibits the replication of simian immunodeficiency virus at an early stage: evidence for a block between attachment and reverse transcription. Virology. 241:156-162  
1997 TOP
Agy, M.B., A. Schmidt, M.J. Florey, B.J. Kennedy, G. Schaffer, M.G. Katze, L. Corey, W.R. Morton, and M.L. Bosch Serial in vivo passage of HIV-1 infection in Macaca nemestrina. Virology. 238:336-343  
Gale, M., Jr. and M.G. Katze What happens inside lentivirus or influenza virus infected cells: insights into regulation of cellular and viral protein synthesis. Methods: Companion Methods Enzymol. 11:383-401  
Gale, M., Jr., M.J. Korth, N.M. Tang, S.-L. Tan, D.A. Hopkins, T.E. Dever, S.J. Polyak, D.R. Gretch, and M.G. Katze Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein. Virology. 230:217-227  
Korth, M.J. and M.G. Katze mRNA metabolism and cancer. p. 265-280. In J. Harford and D. Morris. (ed.), mRNA metabolism & post-transcriptional gene regulation. Wiley-Liss, Inc., New York.  
Melville, M.W., W.J. Hansen, B.C. Freeman, W.J. Welch, and M.G. Katze The molecular chaperone hsp40 regulates the activity of P58IPK, the cellular inhibitor of PKR. Proc. Natl. Acad. Sci. USA. 94:97-102  
1996 TOP
Agy, M.B., C.H. Sherbert, and M.G. Katze Development of an in vitro mRNA degradation assay utilizing extracts from HIV-1- and SIV-infected cells. Virology. 217:158-166  
Gale, M., Jr., S.-L. Tan, M. Wambach, and M.G. Katze Interaction of the interferon-induced PKR protein kinase with inhibitory proteins P58IPK and vaccinia virus K3L is mediated by unique domains: implications for kinase regulation. Mol. Cell. Biol. 16:4172-4181  
Katze, M.G. Translational control in cells infected with influenza virus and reovirus. p. 607-630. In J.W.B. Hershey, M.B. Mathews, and N. Sonenberg. (ed.), Translational control. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.  
Korth, M.J., S. Edelhoff, C.M. Disteche, and M.G. Katze Chromosomal assignment of the gene encoding the human 58-kDa inhibitor (PRKRI) of the interferon-induced dsRNA-activated protein kinase to chromosome 13q32. Genomics. 31:238-239  
Korth, M.J., C.N. Lyons, M. Wambach, and M.G. Katze Cloning, expression, and cellular localization of the oncogenic 58-kDa inhibitor of the RNA-activated human and mouse protein kinase. Gene. 170:181-188  
Polyak, S.J., N. Tang, M. Wambach, G.N. Barber, and M.G. Katze The p58 cellular inhibitor complexes with the interferon-induced, double-stranded RNA-dependent protein kinase, PKR, to regulate its autophosphorylation and activity. J. Biol. Chem. 271:1702-1707  
Tang, N.M., C.Y. Ho, and M.G. Katze The 58-kDa cellular inhibitor of the double stranded RNA-dependent protein kinase requires the tetratricopeptide repeat 6 and DnaJ motifs to stimulate protein synthesis in vivo. J. Biol. Chem. 271:28660-28666  
1995 TOP
Agy, M.B., R.L. Acker, C.H. Sherbert, and M.G. Katze Interferon treatment inhibits virus replication in HIV-1- and SIV-infected CD4+ T-cells by distinct mechanisms: evidence for decreased stability and aberrant processing of HIV-1 proteins. Virology. 214:379-386  
Barber, G.N., R. Jagus, E.F. Meurs, A.G. Hovanessian, and M.G. Katze Molecular mechanisms responsible for malignant transformation by regulatory and catalytic domain variants of the interferon-induced enzyme RNA-dependent protein kinase. J. Biol. Chem. 270:17423-17428  
Barber, G.N., M. Wambach, S. Thompson, R. Jagus, and M.G. Katze Mutants of the RNA-dependent protein kinase (PKR) lacking double-stranded RNA binding domain I can act as transdominant inhibitors and induce malignant transformation. Mol. Cell. Biol. 15:3138-3146  
Katze, M.G. Regulation of the interferon-induced PKR: can viruses cope? Trends Microbiol. 3:75-78  
Lu, Y., M. Wambach, M.G. Katze, and R.M. Krug Binding of the influenza virus NS1 protein to double-stranded RNA inhibits the activation of the protein kinase that phosphorylates the eIF-2 translation initiation factor. Virology. 214:222-228  
Park, Y.-W. and M.G. Katze Translational control by influenza virus: identification of cis-acting sequences and trans-acting factors which may regulate selective viral mRNA translation. J. Biol. Chem. 270:28433-28439.  
1994 TOP
Barber, G.N., M.B. Agy and M.G. Katze Regulation of viral and cellular gene expression in cells infected by animal viruses, including influenza virus and human immunodeficiency virus type 1. p. 141-168. In K. Adolph. (ed.), Methods in virology. Academic Press, Inc., New York.  
Barber, G.N., S. Thompson, T.G. Lee, T. Strom, R. Jagus, A. Darveau, and M.G. Katze The 58-kilodalton inhibitor of the interferon-induced double-stranded RNA-activated protein kinase is a tetratricopeptide repeat protein with oncogenic properties. Proc. Natl. Acad. Sci. USA. 91:4278-4282  
Garfinkel, M.S. and M.G. Katze Influenza virus control of protein synthesis. Scientific American Science & Medicine 64-73  
Kuller, L., R.E. Benveniste, C.-C. Tsai, E.A. Clark, P. Polacino, R. Watanabe, J. Overbaugh, M.G. Katze, and W.R. Morton Intrarectal inoculation of macaques by the siman immunodeficiency vius, SIVmne E11S: CD4+ depletion and AIDS. J. Med. Primatol. 23:397-409  
Lee, T.G. and M.G. Katze Cellular inhibitors of the interferon-induced, dsRNA-activated protein kinase. Prog. Mol. Subcell. Biol. 14:48-65  
Lee, T.G., N. Tang, S. Thompson, J. Miller, and M.G. Katze The 58,000-dalton cellular inhibitor of the interferon-induced double-stranded RNA-activated protein kinase (PKR) is a member of the tetratricopeptide repeat family of proteins. Mol. Cell. Biol. 14:2331-2342  
1993 TOP
Agy, M.B. and M.G. Katze HIV-1 infection of animals: the search for a pathogenesis model continues AIDS. 7:537-542  
Barber, G.N., S. Edelhoff, M.G. Katze, and C.M. Disteche Chromosomal assignment of the interferon-inducible double-stranded RNA-dependent protein kinase to human chromosome 2p21 and mouse chromosome 17 E2. Genomics. 16:765-767  
Barber, G.N., M. Wambach, M.-L. Wong, T.E. Dever, A.G. Hinnebusch, and M.G. Katze Translational regulation by the interferon-induced double-stranded-RNA-activated 68-kDa protein kinase. Proc. Natl. Acad. Sci. USA. 90:4621-4625  
Black, T.L., G.N. Barber, and M.G. Katze Degradation of the interferon-induced 68,000-Mr protein kinase by poliovirus requires RNA. J. Virol. 67:791-800  
Clemens, M.J., J.W.B. Hershey, A.G. Hovanessian, B.L. Jacobs, M.G. Katze, R.J. Kaufman, P. Lengyel, C.E. Samuel, G.C. Sen, and B.R.G. Williams PKR: proposed nomenclature for the RNA-dependent protein kinase induced by interferon. J. Interferon Res. 13:241  
Dever, T.E., J.-J. Chen, G.N. Barber, A.M. Cigan, L. Feng, T.F. Donahue, I.M. London, M.G. Katze, and A.G. Hinnebusch Mammalian eukaryotic initiation factor elF2α kinases functionally substitute for GCN2 protein kinase in the GCN4 translational control mechanism of yeast. Proc. Natl. Acad. Sci. USA. 90:4616-4620  
Diener, T.O., R.W. Hammond, T. Black, and M.G. Katze Mechanisms of viroid pathogenesis: differential activation of the interferon-induced, dsRNA-activated M(r) 68,000 protein kinase by viroid strains of varying pathogenicity. Biochimie 75:533-538  
Frumkin, L.R., M.B. Agy, R.W. Coombs, L. Panther, W.R. Morton, J. Koehler, M.J. Florey, J. Dragavon, A. Schmidt, M.G. Katze, and L. Corey Acute infection of Macaca nemestrina by human immunodeficiency virus type 1. Virology. 195:422-431  
Garfinkel, M.S. and M.G. Katze How does influenza virus regulate gene expression at the level of mRNA translation? Let us count the ways. Gene Expr. 3:109-118.  
Garfinkel, M.S. and M.G. Katze Translational control by influenza virus: selective translation is mediated by sequences within the viral mRNA 5'-untranslated region. J. Biol. Chem. 268:22223-22226  
Katze, M.G. Games viruses play: a strategic initiative against the interferon-induced dsRNA activated 68,000 Mr protein kinase. Semin. Virol. 4:259-268  
Meurs, E.F., J. Galabru, G.N. Barber, M.G. Katze, and A.G. Hovanessian Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase. Proc. Natl. Acad. Sci. USA. 90:232-236.  
1992 TOP
Agy, M.B., L.R. Frumkin, L. Corey, R.W. Coombs, S.M. Wolinsky, J. Koehler, W.R. Morton, and M.G. Katze Infection of Macaca nemestrina by human immunodeficiency virus type-1. Science. 257:103-106  
Barber, G.N., J. Tomita, M.S. Garfinkel, E. Meurs, A. Hovanessian, and M.G. Katze Detection of protein kinase homologues and viral RNA-binding domains utilizing polyclonal antiserum prepared against a baculovirus-expressed ds RNA-activated 68,000-Da protein kinase. Virology. 191:670-679  
Garfinkel, M.S. and M.G. Katze Translational control by influenza virus: selective and cap-dependent translation of viral mRNAs in infected cells J. Biol. Chem. 267:9383-9390  
Katze, M.G The war against the interferon-induced dsRNA-activated protein kinase: can viruses win? J. Interferon Res. 12:241-248  
Koromilas, A.E., S. Roy, G.N. Barber, M.G. Katze, and N. Sonenberg Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase. Science. 257:1685-1689  
Lee, T.G., J. Tomita, A.G. Hovanessian, and M.G. Katze Characterization and regulation of the 58,000-dalton cellular inhibitor of the interferon-induced, dsRNA-activated protein kinase. J. Biol. Chem. 267:14238-14243  
Meurs, E., Y. Watanabe, G.N. Barber, M.G. Katze, K.L. Chong, B.R.G. Williams, and A.G. Hovanessian Constitutive expression of human double-stranded RNA-activated p68 kinase in murine cells mediates phosphorylation of eukaryotic initiation factor 2 and partial resistance to encephalomyocarditis virus growth. J. Virol. 66:5805-5814  
1991 TOP
Agy, M.B., K. Foy, M.J. Gale, R.E. Benveniste, E.A. Clark, and M.G. Katze Viral and cellular gene expression in CD4+ human lymphoid cell lines infected by the simian immunodeficiency virus, SIV/Mne. Virology. 183:170-180  
Barber, G.N., J. Tomita, A.G. Hovanessian, E. Meurs, and M.G. Katze Functional expression and characterization of the interferon-induced double-stranded RNA activated P68 protein kinase from Escherichia coli. Biochemistry. 30:10356-10361  
Ghadge, G., S. Swaminathan, M.G. Katze, and B. Thimmappaya Binding of the adenovirus VAI RNA to the interferon-induced 68-kDa protein kinase correlates with function. Proc. Natl. Acad. Sci. USA 88:7140-7144  
Katze, M.G. and M.B. Agy The regulation of viral and cellular RNA turnover in cells infected by eukaryotic viruses including human immunodeficiency virus HIV-1. p. 332-346. In R.E. Thach. (ed.), Translationally regulated genes in higher eukaryotes. S Karger AG, Basel  
Katze, M.G. and R.M. Krug Translational control in influenza virus-infected cells. p. 265-277. In R.E. Thach. (ed.), Translationally regulated genes in higher eukaryotes. S Karger AG, Basel  
Katze, M.G., M. Wambach, M.-L. Wong, M. Garfinkel, E. Meurs, K. Chong, B.R.G. Williams, A.G. Hovanessian, and G.N. Barber Functional expression and RNA binding analysis of the interferon-induced, double-stranded RNA-activated, 68,000-Mr protein kinase in a cell-free system. Mol. Cell. Biol. 11:5497-5505  
Roy, S., M.B. Agy, A.G. Hovanessian, N. Sonenberg, and M.G. Katze The integrity of the stem structure of human immunodeficiency virus type 1 Tat-responsive sequence RNA is required for interaction with the interferon-induced 68,000-Mr protein kinase. J. Virol. 65:632-640  
1990 TOP
Agy, M.B., M. Wambach, K. Foy, and M.G. Katze Expression of cellular genes in CD4-positive lymphoid cells infected by the human immunodeficiency virus, HIV-1: evidence for a host protein synthesis shutoff induced by cellular mRNA degradation. Virology. 177:251-258  
Coombs, R. and M.G. Katze HIVs and related simian retroviruses. p. 47-60. In K.K. Holmes. (ed.), AIDS Dx/Rx. McGraw Hill, New York  
Katze, M.G. and M.B. Agy Regulation of viral and cellular RNA turnover in cells infected by eukaryotic viruses including HIV-1. Enzyme. 44:332-346  
Katze, M.G. and R.M. Krug Translational control in influenza virus-infected cells. Enzyme. 44:265-277  
Kuller, L., W.R. Morton, R.E. Benveniste, C.-C. Tsai, E. Clark, M. Gale, S.-L. Hu, M. Thouless, and M.G. Katze Inoculation of Macaca fascicularis with simian immunodeficiency virus SIVMne: Immunologic, serologic and pathologic changes. J. Med. Primatol. 19:367-380  
Lee, T.G., J. Tomita, A.G. Hovanessian, and M.G. Katze Purification and partial characterization of a cellular inhibitor of the interferon-induced protein kinase of Mr 68,000 from influenza virus-infected cells. Proc. Natl. Acad. Sci. USA. 87:6208-6212  
Roy, S., M.G. Katze, N.T. Parkin, I. Edery, A.G. Hovanessian, and N. Sonenberg Control of the interferon-induced 68-kilodalton protein kinase by the HIV-1 tat gene product. Science. 247:1216-1219  
1989 TOP
Black, T., B. Safer, A.G. Hovanessian, and M.G. Katze The cellular 68,000 Mr protein kinase is highly autophosphorylated and activated yet significantly degraded during poliovirus infection: implications for translational regulation. J. Virol. 63:2244-2252  
Galabru, J., M.G. Katze, N. Robert, and A.G. Hovanessian The binding of double-stranded RNA and adenovirus VAI RNA to the interferon-induced protein kinase. Eur. J. Biochem. 178:581-589  
Katze, M.G., J. Lara, and M. Wambach Nontranslated cellular mRNAs are associated with cytoskeletal framework in influenza virus or adenovirus infected cells. Virology. 169:312-322  
Krug, R.M., F. Alonso-Caplen, I. Julkunen and M.G. Katze Expression and replication of the influenza virus genome. p. 89-152. In R.M. Krug. (ed.), Influenza viruses. Plenum Publishing Corp., New York  
Morton, W.R., L. Kuller, R.E. Benveniste, E.A. Clark, C.-C. Tsai, M.J. Gale, M. Thouless, J. Overbaugh, and M.G. Katze Transmission of the simian immunodeficiency virus SIV/Mne in macaques and baboons. J. Med. Primatol. 18:237-245  
1988 TOP
Alonso-Caplen, F.V., M.G. Katze, and R.M. Krug Efficient transcription, not translation, is dependent on adenovirus tripartite leader sequences at late times of infection. J. Virol. 62:1606-1616  
Katze, M.G., J. Tomita, T. Black, R.M. Krug, B. Safer, and A.G. Hovanessian Influenza virus regulates protein synthesis during infection by repressing the autophosphorylation and activity of the cellular 68,000-Mr protein kinase. J. Virol. 62:3710-3717  
1987 TOP
Detjen, B.M., C. St.Angelo, M.G. Katze, and R.M. Krug The three influenza virus polymerase (P) proteins not associated with viral nucleocapsids in the infected cell are in the form of a complex. J. Virol. 61:16-22  
Katze, M.G., D. DeCorato, B. Safer, J. Galabru, and A.G. Hovanessian Adenovirus VAI RNA complexes with the 68,000 Mr protein kinase to regulate its autophosphorylation and activity. EMBO J. 6:689-697  
1986 TOP
Katze, M.G., D. DeCorato, and R.M. Krug Cellular mRNA translation is blocked at both initiation and elongation after infection by influenza virus or adenovirus. J. Virol. 60:1027-1039  
Katze, M.G., B.M. Detjen, B. Safer and R.M. Krug Translational control by influenza virus. p. 115-119. In M. Mathews. (ed.), Translational control. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.  
Katze, M.G., B.M. Detjen, B. Safer, and R.M. Krug Translational control by influenza virus: suppression of the kinase that phosphorylates the alpha subunit of initiation factor eIF-2 and selective translation of influenza viral mRNAs. Mol. Cell. Biol. 6:1741-1750  
1984 TOP
Katze, M.G., Y.T. Chen, and R.M. Krug Nuclear-cytoplasmic transport and VAI RNA-independent translation of influenza viral messenger RNAs in late adenovirus-infected cells. Cell. 37:483-490  
Katze, M.G. and R.M. Krug Metabolism and expression of RNA polymerase II transcripts in influenza virus infected cells. Mol. Cell. Biol. 4:2198-2206  
Krug, R.M., A. Beaton, J. Braam and M.G. Katze Influenza viral RNA transcription. p. 225-255. In Y. Becker. (ed.), Viral messenger RNA. Martinus Nijhoff Publishing, Boston  
1983 TOP
Katze, M.G., H. Persson, B.-M. Johansson, and L. Philipson Control of adenovirus gene expression: cellular gene products restrict expression of adenovirus host range mutants in nonpermissive cells. J. Virol. 46:50-59  
1982 TOP
Katze, M.G., H. Persson, and L. Philipson A novel mRNA and a low molecular weight polypeptide encoded in the transforming region of adenovirus DNA. EMBO J. 1:783-789  
Persson, H., M.G. Katze, and L. Philipson Purification of a native membrane-associated adenovirus tumor antigen. J. Virol. 42:905-917  
Signas, C., M.G. Katze, H. Persson, and L. Philipson An adenovirus glycoprotein binds to heavy chains of class 1 transplantation antigens from mouse and man. Nature. 299:175-178  
Virtanen, A., P. Alestrom, H. Persson, M.G. Katze, and U. Petterson An adenovirus agnogene. Nucleic Acids Res. 10:2539-2548  
1981 TOP
Katze, M.G., H. Persson, and L. Philipson Control of adenovirus early gene expression: a posttranscriptional control mediated by both viral and cellular gene products. Mol. Cell. Biol. 1:807-813.  
Persson, H., M.G. Katze, and L. Philipson Control of adenovirus early gene expression: accumulation of viral mRNA after infection of transformed cells. J. Virol. 40:358-366  
1980 TOP
Beatrice, S.T., M.G. Katze, B.A. Zajac, and R.L. Crowell Induction of neutralizing antibodies by the coxsackievirus B3 virion polypeptide, VP2. Virology. 104:426-438  
Katze, M.G. and R.L. Crowell Immunologic studies of the group B coxsackieviruses by the sandwich enzyme-linked immunosorbent assay (ELISA) and immunoprecipitation. J. Gen. Virol. 50:357-367  
Katze, M.G. and R.L. Crowell Indirect enzyme-linked immunosorbent assay (ELISA) for the detection of coxsackievirus group B antibodies. J. Gen. Virol. 48:225-229  
Cohen, G.H., M.G. Katze, C. Hydrean-Stern, and R.J. Eisenberg Type-common CP-1 antigen of herpes simplex virus is associated with a 59,000-molecular weight envelope glycoprotein. J. Virol. 27:172-181  

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